A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Feb 29, 2016 porcine rubulavirus porpv and swine influenza virus infection causes respiratory disease in pigs. Mar 05, 2015 this page was last edited on 7 march 2015, at 09. Sv5 is a species of the genus rubulavirus which also contains mumps virus and human parainfluenza virus 4 fauquet, 2005. The neurovirulence of the new isolates maintains similar characteristics to those reported more than 30 years ago. Humans, apes, pigs, and dogs serve as natural hosts. Development of a realtime rtpcr method for detection of porcine rubulavirus porv lpmv. Porpv persistent infection could facilitate the establishment of secondary infections.
All structured data from the file and property namespaces is available under the creative commons cc0 license. Feb 29, 2016 read coinfection of classic swine h1n1 influenza virus in pigs persistently infected with porcine rubulavirus, veterinary microbiology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. This virus, which affects pigs, first emerged in the 1980s and has since become a serious concern for the mexican swine industry. Avulavirus, which contains the species newcastle disease virus of poultry as well as various avian paramyxoviruses. Porcine rubulavirusla piedadmichoacanmexico virus porpvlpmv was identified as the causative agent of a viral disease that emerged. Development of a realtime rtpcr method for detection of. No immunofluorescence was seen in cells when the primary mab was omitted, or in mockinfected cells. Examples of paramyxovirinae genera include rubulavirus, which is composed of several species of human parainfluenza viruses and the mumps viruses. Purification of porcine rubulavirus attachment protein by isoelectric focusing. Achimota rubulavirus 1 achimota rubulavirus 2 bat mumps rubulavirus human rubulavirus 2 human rubulavirus 4 mammalian rubulavirus 5 mapuera rubulavirus menangle rubulavirus mumps rubulavirus porcine rubulavirus simian rubulavirus sosuga rubulavirus teviot rubulavirus tioman. Rubulavirus is a descriptor in the national library of medicines controlled vocabulary thesaurus, mesh medical subject headings.
Porcine rubulavirus porpv infection emerged spontaneously in pigs in mexico in the early 1980s. Rubulavirus porcino, virus lpm, sindrome del ojo azul, virus. Molecular characterization of the hemagglutininneuraminidase. Porcine rubulavirus article about porcine rubulavirus by. Molecular and epidemiological studies of porcine rubulavirus.
Respiratory disease in growing pigs after porcine rubulavirus experimental. In immunofluorescence assays using a monoclonal antibody mab against the hn protein at 560 min postinfection early infection, a diffuse immunofluorescence was observed near the cell membrane and adjacent to the nuclear membrane. Rubulavirus definition of rubulavirus by medical dictionary. Punctate immunofluorescence was apparent at the external surface of the cytoplasmic membrane when lpmvinfected pk15 cells were incubated with the mab against the hn protein of lpmv 5 min p. Mumps is a contagious vaccinepreventable disease, caused by mumps virus muv, a member of the family paramyxoviridae. Genetic and antigenic changes in porcine rubulavirus ncbi. Author links open overlay panel pablo hernandezjauregui a b alia yacoub a seamus kennedy c bill curran c carlos tellez b martin svenda a leif ljung d jorge morenolopez a. Files are available under licenses specified on their description page. The disease is generally mild, but in some cases can be associated with. Help pages, faqs, uniprotkb manual, documents, news archive and biocuration projects.
Structurefunction analysis of two variants of mumps virus hemagglutininneuraminidase protein purification and characterization of the hemagglutininneuraminidase of porcine rubulavirus lpmv. The v protein plays a role in inhibition of mda5 antiviral signaling. Coinfection of classic swine h1n1 influenza virus in pigs. Experimental infection with recent porcine rubulavirus strains causes acute neurologic disease in pigs viral distribution were identified in nervous, lymphatic, and respiratory systems of the piglets. Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.
Blue eye disease is typically characterized by encephalitis, respiratory disease and high. Las alteraciones reproductivas en sementales incluyen epididimitis y atrofia testicular. Since the report of the initial outbreak of the disease, only one fulllength genome from a strain isolated in 1984 porpvlpmv1984 has been sequenced. Porcine rubulavirus infection, or blue eye disease, is an illness that has been reported only from mexico. The v protein blocks also the type i and ii interferon signaling pathways by interacting with and inhibiting host stat1 and stat2. Hostvirus interaction inhibition of host interferon induction. Etiology porcine rubulavirus porv is an enveloped rna virus in the genus rubulavirus, family paramyxoviridae. Enfermedad del ojo azul by iowa state university center for. Porcine rubulavirus infection iowa state university. Cuevasromero s1, blomstrom al, alvarado a, hernandezjauregui p, riverabenitez f, ramirezmendoza h, berg m. There are five subgroups classified based on the hemagglutininneuraminidase hn gene.
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